RP20527 β-Amyloid (1-42), human
RP20527 β-Amyloid (1-42), human
产品概述
| 产品概述 | This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer’s disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the ‘longer forms’ of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors. |
| Cas No | 107761-42-2 |
| Sequence | |
| Sequence Shortening | DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
| Molecular Formula | C203H311N55O60S1 |
| Molecular Weight | 4514.1 |
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产品属性
| Purity | > 95% |
| Solubility | Soluble in 3% ammonia water under 1mg/ml |
| 产品形式 | Lyophilized |
| 储存条件 | Store at -20°C |
