Z05341 GDF15, His, Human

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Z05341 GDF15, His, Human

Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.

产品简介
SpeciesHuman
Protein Construction
HisGDF15 (Ala197-Ile308)Accession # Q99988-1
N-termC-term
Purity> 95% as determined by Bis-Tris PAGE
Endotoxin LevelLess than 1EU per μg by the LAL method.
Biological ActivityMeasured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression SystemE.coli
Theoretical Molecular Weight13.5 kDa
Apparent Molecular WeightThe protein migrates to 15-16 kDa based on Bis-Tris PAGE result.
FormulationLyophilized from 0.22μm filtered solution in 50mM HAc (pH 2.9).
ReconstitutionCentrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 50mM HAc (pH 2.9).
Storage & StabilityUpon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.