The GenScript Protein A/G MagBeads MX are ideal for small‐scale purification of antibodies from plasma, serum, ascites, and cell culture.
The Protein A/G is a genetically engineered protein (MW≈43 kDa) that combines the IgG binding sites of both Protein A and Protein G. It contains four Fc‐binding domains from Protein A and two from Protein G, making it a universal tool to bind and purify immunoglobulins (IgGs). GenScript’s Protein A/G MagBeads MX have Protein A/G pre-coupled on the surface of superparamagnetic beads. To purify antibodies, a sample containing the antibody of interest is incubated with the Protein A/G MagBeads MX. The antibody binds to the Protein A/G on the beads during a short incubation. This is followed by washing the beads to remove non-specifically bound materials, and eluting the purified antibody. Magnetic separation simplify purification process by eliminating the need for centrifugation, minimizes sample loss and removes the excessive steps of a traditional centrifugation-based purification method.
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